Quantum mechanic glimpse into peptide bond formation within the ribosome shed light on origin of life
نویسنده
چکیده
This article describes a rare, however extremely pleasing, scientific study originated by Prof. Louis Massa during a friendly discussion, which yielded an insightful understanding of one of the two major ribosome functions, namely peptide bond formation. It demonstrates how elaborate, creative approach to the investigation of the location of the actual reaction of the formation of peptide bonds within the ribosomal active site was incorporated into scholarly argumentation on major issues concerning origin of life, including the question: what was first, the genetic code or its products?
منابع مشابه
Chapter Six Glimpse into the Origin of Life
The ribosome is an essential universal cellular apparatus common to all life forms. This molecular assembly decodes the genetic information and catalyzes peptide bond formation. Analyses of all of the known threedimensional structures of ribosomes revealed that the major ribosomal functions are performed by the ribosomal RNA, in accordance with the suggestion that RNA existed before proteins. C...
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